{"id":8102,"date":"2023-11-05T13:33:53","date_gmt":"2023-11-05T12:33:53","guid":{"rendered":"https:\/\/www.roleca.com\/acid-blockers-and-heartburn\/"},"modified":"2026-10-29T09:08:26","modified_gmt":"2026-10-29T08:08:26","slug":"acid-blockers-and-heartburn","status":"publish","type":"page","link":"https:\/\/www.roleca.com\/en\/healthy-digestion\/heartburn\/acid-blockers-and-heartburn\/","title":{"rendered":"Acid Blockers and Heartburn"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-14qbdb-0e0ca6127a950559eaa98a66a82d2001\">\n.avia-section.av-14qbdb-0e0ca6127a950559eaa98a66a82d2001{\nbackground-color:var(--green2);\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen_web.jpg), linear-gradient( to bottom, var(--green2), var(--green1) );\nbackground-position:50% 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class='avia_textblock'  itemprop=\"text\" ><h1>Acid Blockers and Their Interaction with Heartburn<\/h1>\n<p>Colloquially known as acid blockers, proton pump inhibitors (PPIs), as the name suggests, are medications that work by inhibiting the proton pump.<\/p>\n<p>By lowering stomach acid levels, PPIs are used to treat frequent <a href=\"https:\/\/www.roleca.com\/en\/healthy-digestion\/heartburn\/\">heartburn<\/a> and more severe, acid-related conditions. PPIs deactivate the pumps in the stomach that produce excess acid, thus acting as acid blockers.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ku9zhndp-f61c697edd501fbea97c8d457420d4ec\">\n.avia-image-container.av-ku9zhndp-f61c697edd501fbea97c8d457420d4ec img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-ku9zhndp-f61c697edd501fbea97c8d457420d4ec .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-ku9zhndp-f61c697edd501fbea97c8d457420d4ec av-styling- avia-align-center  avia-builder-el-5  el_after_av_textblock  el_before_av_hr  img_rahmen'   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-8103 avia-img-lazy-loading-not-8103 avia_image ' src=\"https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web.jpg\" alt='stomach-with-heartburn' title='stomach-with-heartburn'  height=\"1080\" width=\"1980\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web.jpg 1980w, https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web-300x164.jpg 300w, https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web-1030x562.jpg 1030w, https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web-768x419.jpg 768w, https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web-1536x838.jpg 1536w, https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web-1500x818.jpg 1500w, https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma-sodbrennen-magen-web-705x385.jpg 705w\" sizes=\"(max-width: 1980px) 100vw, 1980px\" \/><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lolglvw2-055f3a2efb7fe32562ffccbb1f926493\">\n#top .hr.hr-invisible.av-lolglvw2-055f3a2efb7fe32562ffccbb1f926493{\nheight:30px;\n}\n<\/style>\n<div  class='hr av-lolglvw2-055f3a2efb7fe32562ffccbb1f926493 hr-invisible  avia-builder-el-6  el_after_av_image  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<section  class='av_textblock_section av-ku9zg2ec-40-573294944c74b4fb0261d0496f122016 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h2>Dependence on PPIs<\/h2>\n<p>A particularly critical aspect that has received increased public attention in recent years is the potential dependence on PPIs (proton pump inhibitors). It is important to distinguish between physical dependence and a true &#8220;addiction.&#8221; With PPIs, it is a so-called &#8220;rebound&#8221; phenomenon, which is also observed when PPI medication is abruptly discontinued.  <\/p>\n<h3>The Rebound Phenomenon<\/h3>\n<p>When people take PPIs for an extended period and then suddenly stop, they may experience increased acid production\u2014an effect known as &#8220;rebound hypersecretion.&#8221; This means that for a certain time after discontinuing the medication, the stomach produces more acid than before the PPI therapy began. This can cause symptoms of heartburn or acid reflux to temporarily worsen. For the affected individual, it may seem as if the body is &#8220;craving&#8221; the medication, although it is actually just a temporary overreaction of the stomach. This was particularly demonstrated in a 2009 study conducted at the University of Copenhagen. Participants who had not previously suffered from acid reflux (heartburn, indigestion, and acid regurgitation) received prescription PPI medications for two months. After discontinuing the medication, these otherwise healthy adult patients began to develop acid reflux symptoms\u2014and ultimately produced even more stomach acid than before. Researchers found that the &#8220;rebound&#8221; effect can last for up to three months.       <\/p>\n<h3>Possible Solutions<\/h3>\n<ol>\n<li>Instead of abruptly stopping PPIs, it can be helpful to gradually reduce the dose. This gives the body an opportunity to slowly adapt to the altered acid production, minimizing the risk of a rebound. <\/li>\n<li>Switching to so-called H2 blockers, another class of acid suppressants, can serve as a transitional solution in some cases. They are not as strong as acid blockers (PPIs), but can offer some relief and facilitate the transition. <\/li>\n<li>It is important for doctors to inform their patients about the potential rebound phenomenon and support them in deciding whether to discontinue or continue using acid blockers (PPIs) long-term.<\/li>\n<\/ol>\n<h3>Important Message<\/h3>\n<p>Concerns about medication dependence on PPIs should not deter people from using these medications when needed and recommended by a doctor. However, it is important to be aware of potential long-term effects and to create a plan with a doctor if discontinuing the medication is being considered. <\/p>\n<p>Overall, despite concerns, PPIs offer many benefits and have improved the lives of many people with severe heartburn and other acid-related complaints. However, responsible and informed use is essential to ensure that the benefits outweigh the potential risks.<\/p>\n<\/div><\/section><\/p><\/div><div class='av-flex-placeholder'><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-22lbze-394068518114cb0f6aab8df72f10ad70\">\n#top .flex_column_table.av-equal-height-column-flextable.av-22lbze-394068518114cb0f6aab8df72f10ad70{\nmargin-top:-5px;\nmargin-bottom:0px;\n}\n.flex_column.av-22lbze-394068518114cb0f6aab8df72f10ad70{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-22lbze-394068518114cb0f6aab8df72f10ad70 av_one_fifth  avia-builder-el-8  el_after_av_three_fifth  avia-builder-el-last  flip-mobile av-break-at-tablet flex_column_table_cell av-equal-height-column av-align-middle av-zero-column-padding  '     ><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->[av_section min_height='' min_height_pc='25' min_height_px='500px' padding='default' custom_margin='0px' custom_margin_sync='true' color='main_color' background='bg_color' custom_bg='var(--green1)' background_gradient_color1='var(--green100)' background_gradient_color2='var(--green1)' background_gradient_direction='vertical' src='' attachment='' attachment_size='' attach='scroll' position='bottom right' repeat='no-repeat' video='' video_ratio='16:9' overlay_opacity='0.5' overlay_color='' overlay_pattern='' overlay_custom_pattern='' shadow='no-border-styling' bottom_border='no-border-styling' bottom_border_diagonal_color='#333333' bottom_border_diagonal_direction='' bottom_border_style='' custom_arrow_bg='' id='' custom_class='column_flex_reorder' aria_label='' av_element_hidden_in_editor='0' av_uid='av-9ypwv']\n\n[av_one_full first min_height='av-equal-height-column' vertical_alignment='av-align-top' space='' row_boxshadow_color='' row_boxshadow_width='10' margin='0px' margin_sync='true' mobile_breaking='av-break-at-tablet' border='' border_color='' radius='0px' radius_sync='true' padding='0px' padding_sync='true' column_boxshadow_color='' column_boxshadow_width='10' background='bg_color' background_color='' background_gradient_color1='' background_gradient_color2='' background_gradient_direction='vertical' src='' attachment='' attachment_size='' background_position='top left' background_repeat='no-repeat' highlight_size='1.1' animation='' link='' linktarget='' link_hover='' title_attr='' alt_attr='' mobile_display='' id='' custom_class='flip-mobile' aria_label='' av_uid='av-sifpz']\n\n[av_textblock size='' av-medium-font-size='' av-small-font-size='' av-mini-font-size='' font_color='' color='' id='' custom_class='' av_uid='av-kuzes252' admin_preview_bg='']\n<h3>Learn more about the following topics<\/h3>\n[\/av_textblock]\n\n[\/av_one_full][av_one_third first min_height='av-equal-height-column' vertical_alignment='av-align-top' space='' row_boxshadow_color='#757575' row_boxshadow_width='10' margin='0px' margin_sync='true' mobile_breaking='av-break-at-tablet' border='' border_color='' radius='0px' radius_sync='true' padding='0px' padding_sync='true' column_boxshadow_color='' column_boxshadow_width='10' background='bg_color' background_color='' background_gradient_color1='' background_gradient_color2='' background_gradient_direction='vertical' src='' attachment='' attachment_size='' background_position='top left' background_repeat='no-repeat' highlight_size='1.1' animation='' link='' linktarget='' link_hover='' title_attr='' alt_attr='' mobile_display='' id='' custom_class='img_rahmen' aria_label='' av_uid='av-sifpz-5']\n\n[av_image_txt src=\"https:\/\/www.roleca.com\/wp-content\/uploads\/169_ROLECA_Verdauungsbeschwerden.jpg\" attachment=\"2213\" attachment_size=\"full\" copyright=\"\" caption=\"yes\" styling=\"\" align=\"center\" font_size=\"\" overlay_opacity=\"0.4\" overlay_color=\"#000000\" overlay_text_color=\"#ffffff\" animation=\"no-animation\" hover=\"\" appearance=\"\" link=\"\" target=\"\" title_attr=\"\" alt_attr=\"bl\u00e4hungen und v\u00f6llegef\u00fchl\" lazy_loading=\"disabled\" id=\"\" custom_class=\"\" av_element_hidden_in_editor=\"0\" av_uid=\"av-kuza838l\" admin_preview_bg=\"\"]\n<h4>Bloating and Fullness<\/h4>\nIn a survey, 7 out of 10 respondents reported having suffered from digestive issues in the past 12 months. Bloating and fullness are often leading symptoms that are uncomfortable for those affected. You can find more detailed information and a suggested treatment here.  \n\n<span class=\"rpbutton\"><a href=\"https:\/\/www.roleca.com\/verdauung\/verdauungsprobleme\/#haeufigesymptomeverdauungsprobleme\">Learn More<\/a><\/span>\n[\/av_image_txt]\n\n[\/av_one_third][av_one_third min_height='av-equal-height-column' vertical_alignment='av-align-top' space='' row_boxshadow_color='#757575' row_boxshadow_width='10' margin='0px' margin_sync='true' mobile_breaking='av-break-at-tablet' border='' border_color='' radius='0px' radius_sync='true' padding='0px' padding_sync='true' column_boxshadow_color='' column_boxshadow_width='10' background='bg_color' background_color='' background_gradient_color1='' background_gradient_color2='' background_gradient_direction='vertical' src='' attachment='' attachment_size='' background_position='top left' background_repeat='no-repeat' highlight_size='1.1' animation='' link='' linktarget='' link_hover='' title_attr='' alt_attr='' mobile_display='' id='' custom_class='img_rahmen' aria_label='' av_uid='av-sifpz-4']\n\n[av_image_txt src=\"https:\/\/www.roleca.com\/wp-content\/uploads\/rolecapharma_21968563.jpg\" attachment=\"2199\" attachment_size=\"full\" copyright=\"\" caption=\"yes\" styling=\"\" align=\"center\" font_size=\"\" overlay_opacity=\"0.4\" overlay_color=\"#000000\" overlay_text_color=\"#ffffff\" animation=\"no-animation\" hover=\"\" appearance=\"\" link=\"\" target=\"\" title_attr=\"\" alt_attr=\"darmmirkobiom\" img_scrset=\"\" lazy_loading=\"disabled\" id=\"\" custom_class=\"\" template_class=\"\" av_element_hidden_in_editor=\"0\" av_uid=\"av-kuza838l-3\" sc_version=\"1.0\" admin_preview_bg=\"\"]\n<h4>The Gut Microbiome<\/h4>\nCentral functions such as breaking down food, providing essential vitamins and nutrients, and protecting against pathogens and strengthening the immune system are just an initial indication of how important the gut microbiome is for holistic health.\n\n<span class=\"rpbutton\"><a href=\"https:\/\/www.roleca.com\/verdauung\/mikrobiom\/\">Learn More<\/a><\/span>\n[\/av_image_txt]\n\n[\/av_one_third][av_one_third min_height='av-equal-height-column' vertical_alignment='av-align-top' space='' row_boxshadow_color='#757575' row_boxshadow_width='10' margin='0px' margin_sync='true' mobile_breaking='av-break-at-tablet' border='' border_color='' radius='0px' radius_sync='true' padding='0px' padding_sync='true' column_boxshadow_color='' column_boxshadow_width='10' background='bg_color' background_color='' background_gradient_color1='' background_gradient_color2='' background_gradient_direction='vertical' src='' attachment='' attachment_size='' background_position='top left' background_repeat='no-repeat' highlight_size='1.1' animation='' link='' linktarget='' link_hover='' title_attr='' alt_attr='' mobile_display='' id='' custom_class='img_rahmen' aria_label='' av_uid='av-sifpz-2']\n\n[av_image_txt src=\"https:\/\/www.roleca.com\/wp-content\/uploads\/roleca_laxan_brausetablette_anwendung_web.jpg\" attachment=\"3909\" attachment_size=\"full\" copyright=\"\" caption=\"yes\" styling=\"\" align=\"center\" font_size=\"\" overlay_opacity=\"0.4\" overlay_color=\"#000000\" overlay_text_color=\"#ffffff\" animation=\"no-animation\" hover=\"\" appearance=\"\" link=\"\" target=\"\" title_attr=\"\" alt_attr=\"tr\u00e4ger darm ankurbeln\" img_scrset=\"\" lazy_loading=\"disabled\" id=\"\" custom_class=\"\" template_class=\"\" av_element_hidden_in_editor=\"0\" av_uid=\"av-kuza838l-1\" sc_version=\"1.0\" admin_preview_bg=\"\"]\n<h4>Roleca\u00ae Macrogol Effervescent Tablets<\/h4>\nStaying active is a commonly heard piece of advice for general health. Movement is beneficial and contributes to a healthy lifestyle, especially outdoors. Our gut also benefits from a change of pace from long periods of sitting. But what to do when the gut is sluggish?\n\n<span class=\"rpbutton\"><a href=\"https:\/\/www.roleca.com\/produkte\/macrogol\/\">Learn More<\/a><\/span>\n[\/av_image_txt]\n\n[\/av_one_third][\/av_section]<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":14,"featured_media":0,"parent":8360,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8102","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/pages\/8102","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/comments?post=8102"}],"version-history":[{"count":2,"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/pages\/8102\/revisions"}],"predecessor-version":[{"id":8105,"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/pages\/8102\/revisions\/8105"}],"up":[{"embeddable":true,"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/pages\/8360"}],"wp:attachment":[{"href":"https:\/\/www.roleca.com\/en\/wp-json\/wp\/v2\/media?parent=8102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}